Polymorphism: CHIT1 24-bp duplication





Factor:
- Symbol: CHIT1
- Name: chitinase 1 (chitotriosidase)
- Entrez ID: 1118
- Ensembl ID: ENSG00000133063


Description:

Candidate gene

Ethnicity: Tunisian, Greek, Italian
Age of cases: Mean age 97.6
Shorter lived allele: Absence of duplication
Longer lived allele: Presence of duplication

Statistics
- Number of cases/controls: 129 vs 129 (initial) | 29 versus 129 (replication)
- p-value: 0.05
- Significant: Yes

Study Design
- Study type: Candidate Region/Gene
- Technology: PCR & gel electrophoresis

Reference:
19881466: Human chitotriosidase polymorphism is associated with human longevity in Mediterranean nonagenarians and centenarians.

Choice: Curate_Johnny
Created: June 30, 2013, 11:58 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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