Polymorphism: SV-6


Variant Type: Deletion
Location: Ex6-35

Factor:
- Symbol: CLU
- Name: clusterin
- Entrez ID: 1191
- Ensembl ID: ENSG00000120885


Description:

Candidate gene. Compares "A" vs "B" alleles of SV-6. Subsequent sequence analysis revealed that the detected variant presented a noncoding thymidine (T) deletion at the intron sequence, 35 nucleotides up- stream from exon 6 (termed SV-6B).

Ethnicity: Greek, Italian
Age of cases: 99–107

Statistics
- Number of cases/controls: 49 vs 27 vs 20 (initial)
- p-value: 1.0
- Significant: No

Study Design
- Study type: Candidate Region/Gene
- Technology: PCR & gel electropheresis

Reference:
16804001: Reduced expression levels of the senescence biomarker clusterin/apolipoprotein j in lymphocytes from healthy centenarians.

Choice: Curate_Johnny
Created: June 30, 2013, 11:58 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.

Edit (Admin) | Delete