Polymorphism: rs12050077
rs12050077
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 1p13
Factor:
- Symbol: TSHR
- Name: thyroid stimulating hormone receptor
- Entrez ID: 7253
- Ensembl ID: ENSG00000165409
Factors:
TSH-B
thyroid stimulating hormone, beta
(
7252
/
ENSG00000134200
)
Description:
Ethnicity:
Ashkenazi Jewish
Age of cases: Median age 97
Shorter lived allele: G
Longer lived allele: A
Finding: Positive
Statistics
- Number of cases/controls: 232 vs 163 (initial)
- Odds ratio: 1.68
- p-value:
0.0001
[0.0001]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR & sequencing
Reference:
19837933: Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.
Choice: Curate_Johnny
Created: June 30, 2013, 11:53 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.
Edit
(
Admin) |
Delete