Polymorphism: rs10149689
rs10149689 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: TSHR
- Name: thyroid stimulating hormone receptor
- Entrez ID: 7253
- Ensembl ID: ENSG00000165409


Description: Ethnicity: Ashkenazi Jewish
Age of cases: Median age 97
Shorter lived allele: A
Longer lived allele: G
Finding: Positive

Statistics
- Number of cases/controls: 232 vs 163 (initial)
- Odds ratio: 1.56
- p-value: 0.001 [0.001]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR & sequencing

Reference:
19837933: Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.

Choice: Curate_Johnny
Created: June 30, 2013, 11:53 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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