Denigma Buck Institute Health Extension
Polymorphism: rs2701858, rs9486902
rs2701858, ( SNPedia | 23andMe )
rs9486902 ( SNPedia | 23andMe )

Variant Type:


Factors:
  • FOXO1A forkhead box O1 ( 2308 / ENSG00000150907 )
  • FOXO3A forkhead box O3 ( 2309 / ENSG00000118689 )


    • Description:

    180 pairs of interacting FOXO SNPs were tested; this was the only significant result.

    Ethnicity: Danish
    Age of cases: 92+
    Finding: Positive

    Statistics
    - Number of cases/controls: 1088 (initial)
    - Odds ratio: 3.23
    - Odds ratio type:
    - p-value: 0.0001 [0.0001]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology:

    Reference:
    23607278: A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family.

    Choice: Curate
    Created: Aug. 31, 2014, 9:35 p.m.
    Updated: Sept. 4, 2014, 9:44 p.m.

    Edit (Admin) | Delete