Denigma Buck Institute Health Extension
Polymorphism: rs680109
rs680109 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 11q22

Factor:
- Symbol: GRIA4
- Name: glutamate receptor, ionotrophic, AMPA 4
- Entrez ID: 2893
- Ensembl ID: ENSG00000152578

Factors:
  • GRIA4 glutamate receptor, ionotrophic, AMPA 4 ( 2893 / ENSG00000152578 )


    • Description:

    P value for association with age at death.

    Ethnicity: American, British
    Age of cases: Age range 50-108; mean age at death 80.2
    Shorter lived allele: C
    Longer lived allele: A
    Finding: Positive

    Statistics
    - Number of cases/controls: 1364 (initial)
    - Odds ratio type: N/A
    - p-value: 2.52e-05 [0.0000252]
    - Significant: Nominally yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina 300, Illumina 610

    Reference:
    22445811: Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

    Choice: Clean
    Created: Aug. 14, 2013, 1:16 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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