Polymorphism: Mitochondrial haplogroups
Variant Type: Locus
Location: MT
Factor:
- Symbol: mtDNA
Description:
Differences between mtDNA haplogroup frequencies were significantly different between groups of ages (p=0.01).
Compared to the old, haplogroup H was less frequent than among the middle-aged subjects and infants (p=0.001 and p=0.00001), whereas haplogroups U and J were more common.
Ethnicity:
Finn
Age of cases: 90-91
Shorter lived allele: H
Longer lived allele: U, J, K
Finding: Positive
Statistics
- Number of cases/controls: 225 (cases) vs 400 middle aged vs 257 infants (initial)
- p-value:
0.001
- Significant: Yes
Study Design
- Study type: Mitochondrial Haplogroup
- Technology: PCR-RFLP
Reference:
12483296: Mitochondrial DNA polymorphisms associated with longevity in a Finnish population.
Choice: Clean
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:06 p.m.
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