Denigma Buck Institute Health Extension
Polymorphism: rs17811551
rs17811551 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 5q12

Factor:
- Symbol: ADAMTS6
- Name: ADAM metallopeptidase with thrombospondin type 1 motif, 6
- Entrez ID: 11174
- Ensembl ID: ENSG00000049192

Factors:
  • ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 ( 11174 / ENSG00000049192 )


    • Description:

    P value for association with age at death.

    Ethnicity: American, British
    Age of cases: Age range 50-108; mean age at death 80.2
    Shorter lived allele: T
    Longer lived allele: C
    Finding: Positive

    Statistics
    - Number of cases/controls: 1364 (initial)
    - Odds ratio type: N/A
    - p-value: 3.74e-06 [0.00000374]
    - Significant: Nominally yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina 300, Illumina 610

    Reference:
    22445811: Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

    Choice: Clean
    Created: Aug. 14, 2013, 1:16 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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