Polymorphism: rs73598374
rs73598374 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: ADA
- Name: adenosine deaminase
- Entrez ID: 100
- Ensembl ID: ENSG00000196839


Description:

Applies to males only.

Ethnicity: Italian
Age of cases: >88
Shorter lived allele: G*/G*
Longer lived allele: A*+
Finding: Positive

Statistics
- Number of cases/controls: 97 vs 261 (initial)
- Odds ratio: 0.32
- p-value: 0.0056 [0.0056]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
21865054: Age- and gender-specific epistasis between ADA and TNF-α influences human life-expectancy.

Choice: Curate
Created: Aug. 11, 2013, 2:36 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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