Polymorphism: rs61733139
rs61733139 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: MTTP
- Name: microsomal triglyceride transfer protein
- Entrez ID: 4547
- Ensembl ID: ENSG00000138823


Description:

Based on Leiden Longevity Study. Cross-sectional association analysis used to test for association of the MTP gene with longevity. "The allele frequencies did not differ between the case and control groups…"

Initial number refers to nonagenarian sib pairs vs partners of the offspring of nonagenarian sib pairs

Ethnicity: Dutch
Age of cases: Mean age 93.8 ± 3.1
Finding: Negative

Statistics
- Number of cases/controls: 379 vs 251 (initial)
- p-value: 0.57 [0.57]
- Significant: No

Study Design
- Classifications: No Age Effect
- Study type: Candidate Region/Gene
- Technology: PCR based probes

Reference:
16611701: Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies.

Choice: Curate
Created: Aug. 11, 2013, 2:04 a.m.
Updated: Aug. 9, 2014, 11:32 p.m.

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