Polymorphism: C4BQO
Alias: BQ0
Variant Type: Haplotype
Location: 6p21.3
Factor:
- Symbol: C4B
- Name: complement component 4B (Chido blood group)
- Entrez ID: 721
- Ensembl ID: ENSG00000224389
Factors:
CFB
complement factor B
(
629
/
ENSG00000243649
)
Description:
An increase of C4BQO in the older cohort was observed: 2 = 3.9, p = .05), centenarians versus old people (17% vs 9%, X centenarians versus young people (17% vs 11%; X2 = 3.9; p = .04), but this difference was not maintained after correction for the number of alleles examined.
Ethnicity:
Italian
Age of cases: Mean age 101
Finding: Negative
Statistics
- Number of cases/controls: 77 (cases) vs 235 (initial)
- Significant: No
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Restriction fragment analysis
Reference:
10219002: C4, BF, C3 allele distribution and complement activity in healthy aged people and centenarians.
Choice: Clean
Created: Aug. 9, 2013, 8:09 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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