Polymorphism: rs1800795
rs1800795 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: IL6
- Name: interleukin 6 (interferon, beta 2)
- Entrez ID: 3569
- Ensembl ID: ENSG000001

Ethnicity: Italian
Age of cases: 85+
Shorter lived allele: CC (genotype)
Finding: Positive

Statistics
- Number of cases/controls: 244 vs 309 (initial) | 138 vs 98 (replication)
- p-value: 0.006 [0.006 (males)]
- Significant: Yes

Study Design
- Study type: Candidate Region/Gene
- Technology: PCR, restriction digest, gel electrophoresis

Reference:
19377912: Interleukin-6 plasma level increases with age in an Italian elderly population ("The Treviso Longeva"-Trelong-study) with a sex-specific contribution of rs1800795 polymorphism.

Choice: Clean
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.

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