Denigma Buck Institute Health Extension
Polymorphism: rs4952085
rs4952085 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 2p23.1

Factor:
- Symbol: XDH
- Name: xanthine dehydrogenase
- Entrez ID: 7498
- Ensembl ID: ENSG00000158125

Factors:
  • XDH xanthine dehydrogenase ( 7498 / ENSG00000158125 )


    • Description:

    P value reported is min.pval, odds ratio is OR.A.B (from paper)

    Ethnicity: Caucasian
    Age of cases: Median age 104
    Shorter lived allele: A
    Longer lived allele: G
    Finding: Positive

    Statistics
    - Number of cases/controls: 801 vs 914 (initial)
    - Odds ratio: 1.253317347
    - p-value: 0.000933537 [0.000933537]
    - Significant: Nominally yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina: 370 CNV chip v1.0, Human610-Quad v1.0, Human 1 M v1.0

    Reference:
    22279548: Genetic signatures of exceptional longevity in humans.

    Choice: Clean
    Created: July 20, 2013, 10:46 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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