Polymorphism: rs2075650
rs2075650 ( SNPedia | 23andMe )

Location: 19q13

Factor:
- Symbol: TOMM40
- Name: translocase of outer mitochondrial membrane 40 homolog (yeast)
- Entrez ID: 10452
- Ensembl ID: ENSG00000130204

Factors:
  • TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) ( 10452 / ENSG00000130204 )


  • Description:

    P value reported is min.pval, odds ratio is OR.A.B (from paper)

    Ethnicity: Caucasian
    Age of cases: Median age 104
    Shorter lived allele: G
    Longer lived allele: A

    Statistics
    - Number of cases/controls: 801 vs 914 (initial) | 253 vs 341 (replication)
    - Odds ratio: 2.068965519
    - p-value: 2.36e-10 [0.000000000236]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina: 370 CNV chip v1.0, Human610-Quad v1.0, Human 1 M v1.0

    Reference:
    22279548: Genetic signatures of exceptional longevity in humans.

    Choice: Clean
    Created: July 20, 2013, 10:42 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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