Polymorphism: rs2060793
rs2060793 ( SNPedia | 23andMe )

Location: 11p15.2

Factor:
- Symbol: CYP2R1
- Name: cytochrome P450, family 2, subfamily R, polypeptide 1
- Entrez ID: 120227
- Ensembl ID: ENSG00000186104

Factors:
  • CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 ( 120227 / ENSG00000186104 )


  • Description:

    Compared with controls, the offspring had a lower frequency of a genetic variant in the CYP2R1 gene (rs2060793) (p = 0.04).

    odds_ratio = N/A (could not convert string to float: )

    Ethnicity: Dutch
    Age of cases: 59.5 years (offspring of nonagerians)
    Shorter lived allele: A

    Statistics
    - Number of cases/controls: 1038 vs 461 (initial)
    - p-value: 0.04
    - Significant: Yes

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: Illumina Infinium HD Human660W-Quad BeadChips and Illumina OmniExpress BeadChips

    Reference:
    23128285: Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study.

    Choice: Curate
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

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