Polymorphism: HUMTHO1 (STR)
Location: 18p11.32
Factor:
- Symbol: THO
- Name: THO complex 1
- Entrez ID: 9984
- Ensembl ID: ENSG00000079134
Factors:
THO
THO complex 1
(
9984
/
ENSG00000079134
)
Description:
This association may preferentially affect genotype frequencies in male centenarians.
Ethnicity:
Italian
Age of cases: >100
Shorter lived allele: 9-10 (long alleles, homozygous genotype)
Finding: Positive
Statistics
- Number of cases/controls: 196 (143 f, 53 m) vs 358 (296 f; 64 m) (initial)
- p-value:
0.05
[<0.05]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
9887369: Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin) |
Delete