Polymorphism: rs9536314
rs9536314 ( SNPedia | 23andMe )

Location: 13q12

Factor:
- Symbol: KL
- Name: klotho
- Entrez ID: 9365
- Ensembl ID: ENSG00000133116

Factors:
  • KL klotho ( 9365 / ENSG00000133116 )


  • Description:

    Assesment of CVD risk and KL polymorphism.

    Ethnicity: Ashkenazi Jewish
    Age of cases: >95
    Longer lived allele: TG (genotype)
    Finding: Positive

    Statistics
    - Number of cases/controls: 216 vs 309 (initial)
    - p-value: 0.007 [0.007]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    15677572: Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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