Polymorphism: rs1333049
rs1333049
(
SNPedia |
23andMe
)
Variant Type: SNP
Description:
"The frequency of the C allele of rs1333049 was significantly lower in centenarians compared to young controls, whereas AMI patients showed a higher frequency. After adjustment for gender and traditional vascular controls, whereas AMI patients showed a higher frequency. After adjustment for gender and traditional vascular
Ethnicity:
Human
Age of cases: 100–104
Shorter lived allele: C
Finding: Positive
Statistics
- Number of cases/controls: 80 (cases) vs 258 healthy young (initial)
- Odds ratio: 0.64
- Odds ratio type: Longer
- p-value:
0.001
[<0.001]
- Significant: Yes
Study Design
- Study type: Candidate Region/Gene
- Technology: TaqMan SNP genotyping assay
Reference:
20230275: Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity.
Choice: Clean
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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