Denigma Buck Institute Health Extension
Polymorphism: rs429358, rs7412
rs429358, ( SNPedia | 23andMe )
rs7412 ( SNPedia | 23andMe )

Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )


    • Description:

    odds_ratio = 0.39 (1.89) (invalid literal for float(): 0.39 (1.89))

    pvalue = 0.000156 (0.008414) (invalid literal for float(): 0.000156(0.008414))

    Ethnicity: American, Caucasian
    Age of cases: Mean 100,8
    Shorter lived allele: e4
    Longer lived allele: e2

    Statistics
    - Number of cases/controls: 653 (197 m, 456 f) vs non-mentioned (initial) | 564 (92 m, 472 f) vs 564___(Franch Caucasians) (replication)
    - p-value: [0.000156 (0.008414)]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Sequenom's chip-based matrix-assisted laser desorption/ionization time-of-flight MS and RT-PCR

    Reference:
    14615589: Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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