Polymorphism: Q/H 95
Location: 4q24
Factor:
- Symbol: MTP
- Name: microsomal triglyceride transfer protein
- Entrez ID: 4547
- Ensembl ID: ENSG00000138823
Factors:
MTP
microsomal triglyceride transfer protein
(
4547
/
ENSG00000138823
)
Description:
There were several confirmatory studies, one in USA cohort, second - in French. I`ve mentioned French cohort as second study. Noteworthy to say, that highly appreciated (by autors) genotype combination rs2866164 / MTP Q/H95 has no statistically significant differencies in the replication study in French cohort.
pvalue = 0.071 (0.55) (invalid literal for float(): 0.071(0.55))
Ethnicity:
American,
Caucasian
Age of cases: Mean 100,8
Shorter lived allele: Q95
Longer lived allele: H95
Statistics
- Number of cases/controls: 653 (197 m, 456 f) vs non-mentioned (initial)
| 564 (92 m, 472 f) vs 564___(Franch Caucasians) (replication)
- p-value:
[0.071 (0.55)]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Genome-Wide Association Study
- Technology: Sequenom's chip-based matrix-assisted laser desorption/ionization time-of-flight MS and RT-PCR
Reference:
14615589: Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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