Polymorphism: rs326146
rs326146 ( SNPedia | 23andMe )

Location: 5p15.3

Factor:
- Symbol: ADCY2
- Name: adenylate cyclase 2 (brain)
- Entrez ID: 108
- Ensembl ID: ENSG00000078295

Factors:
  • ADCY2 adenylate cyclase 2 (brain) ( 108 / ENSG00000078295 )


  • Description:

    Here were analyzed multiple genes and even SNP combinations, so it is very difficult to make it as a short report. There were 2 types of data for SNPs: as I understood primary and after inheritance fitting modeling. I`ve depicted first one. Also there is no clear description of alleles.

    Ethnicity: Korean
    Age of cases: Mean age 90
    Longer lived allele: A

    Statistics
    - Number of cases/controls: 137 vs 213 (initial)
    - Odds ratio: 1.46
    - p-value: 0.024 [0.024]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Sentrix Array Matrices

    Reference:
    19641380: Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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