Polymorphism: rs429358, rs7412
rs429358,
(
SNPedia |
23andMe
)
rs7412
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Ethnicity:
Ashkenazi Jewish
Age of cases: Mean age 75
Shorter lived allele: e4
Longer lived allele: e2
Finding: Positive
Statistics
- Number of cases/controls: (150 m, 74 f) vs (121 m, 320 f) (initial)
- p-value:
0.025
[0.025]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
15621215: Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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