Denigma Buck Institute Health Extension
Polymorphism: rs12892152
rs12892152 ( SNPedia | 23andMe )

Location: 14q31

Factor:
- Symbol: NRXN3
- Name: neurexin 3
- Entrez ID: 9369
- Ensembl ID: ENSG00000021645

Factors:
  • NRXN3 neurexin 3 ( 9369 / ENSG00000021645 )

    • Ethnicity: Dutch
    Age of cases: Mean age 94
    Longer lived allele: A

    Statistics
    - Number of cases/controls: 403 vs 1670 (initial) | 3746 vs 5912 (replication)
    - Odds ratio: 1.87
    - p-value: 5.78e-05 [5.78x10^-5]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina Infinium HD Human660W-Quad BeadChips; Illumina Infinium II HumanHap550-Duo BeadChips

    Reference:
    21418511: Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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