Polymorphism: rs740746
rs740746
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 10q25.3
Factor:
- Symbol: ADRB1
- Name: adrenergic, beta-1-, receptor
- Entrez ID: 153
- Ensembl ID: ENSG00000043591
Factors:
ADRB1
adrenergic, beta-1-, receptor
(
153
/
ENSG00000043591
)
Description:
Replication Study ethnicity = Southern China Han Chinese. Replication Study age of cases = ≥95 men and ≥100 women, mean age = 101.0 ± 0.16. Odds ratio and P-values of combined studies also appear in paper
Ethnicity:
Chinese
Age of cases: Mean age 102.1±0.20
Finding: Negative
Statistics
- Number of cases/controls: 384 vs 384 (initial)
| 579 vs 644 (replication)
- p-value:
0.556
[0.556]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: Protocol of BigDye v1.1 kit and an ABI 3130XL sequencing system (Applied Biosystems)
Reference:
23020224: Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity.
Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin) |
Delete