Denigma Buck Institute Health Extension
Polymorphism: rs11066301
rs11066301 ( SNPedia | 23andMe )

Location: 12q24

Factor:
- Symbol: PTPN11
- Name: protein tyrosine phosphatase, non-receptor type 11
- Entrez ID: 5781
- Ensembl ID: ENSG00000179295

Factors:
  • PTPN11 protein tyrosine phosphatase, non-receptor type 11 ( 5781 / ENSG00000179295 )

    • Ethnicity: Calabrian
    Age of cases: 90+, median 92

    Statistics
    - Number of cases/controls: 288 vs 554 (initial)
    - p-value: 0.0111 [0.0111]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: allele-specific PCR-based KASPar SNP genotyping system (KBiosciences, Hoddesdon, UK) (Cuppen

    Reference:
    22576335: MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case-control study using a multilocus genotyping.

    Choice: Curate
    Created: July 2, 2013, 2:48 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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