Denigma Buck Institute Health Extension
Polymorphism: rs26802
rs26802 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 3p26-p25

Factor:
- Symbol: GHRL
- Name: ghrelin/obestatin prepropeptide
- Entrez ID: 51738
- Ensembl ID: ENSG00000157017

Factors:
  • GHRL ghrelin/obestatin prepropeptide ( 51738 / ENSG00000157017 )


    • Description:

    Sig. in males

    Ethnicity: Danish
    Age of cases: 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up
    Shorter lived allele: A
    Finding: Positive

    Statistics
    - Number of cases/controls: 1089 (see notes - follow-up study) (initial) | 563 (see notes - follow-up study) (replication)
    - Odds ratio: 2.338
    - p-value: 0.032 [0.032]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene

    Reference:
    22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.

    Choice: Curate
    Created: July 2, 2013, 2:48 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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