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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4646994 | ACE | 2.25 | 0.003 | 834 | — | Brazilian | 10-104 | I | D (only for Gaucho population) | Candidate Region/Gene | 14528043 |
| rs4646994 | ACE | — | 0.04 | 227 Uighur individuals, 108 Kazakh individuals, and 89 Han individuals | — | Chinese | Old: 59-70, Very old 90-113 | I (insertion) | — | Candidate Region/Gene | 11773214 |
| (+)2019 del | ADIPOQ10 | — | 0.05 | 118 centenarians vs 78 unrelated young | — | Ashkenazi Jewish | 95-105 | A | Del/Del | Candidate Region/Gene | 18511746 |
| SV-6 | CLU | — | 1.0 | 49 vs 27 vs 20 | — | Greek, Italian | 99–107 | — | — | Candidate Region/Gene | 16804001 |
| rs72533289 | KIR2DS4 | — | 1.0 | 180 vs 180 | — | Irish | Mean age 89 | — | — | Candidate Region/Gene | 15130674 |