Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
TNF haplotypes TNF — 0.01 60 vs 50 — Bulgarian Age range: 65-99 — −1031 C/C, −863 C/A, −857 C/C, −308 G/G, +489 G/G Candidate Region/Gene 21299522
Not specified IL2 — 0.05 470 vs 120 — Italian, Bulgarian Age range: 65-99 — — Candidate Region/Gene 21299522
Not specified IFNG — 0.05 707 vs 339 — Turkish, Polish, Italian, Bulgarian Age range: 65-99 — — Candidate Region/Gene 21299522
IL10 haplotypes IL10 — 0.05 60 vs 60 — Bulgarian Age range: 65-99 — −1082G, −819C, -592C Candidate Region/Gene 21299522
TGFB1 haplotypes TGFB1 — 0.05 297 vs 130 — Turkish, Bulgarian Age range: 65-99 codon 10 C/C, codon 25 G/G — Candidate Region/Gene 21299522
TGFB1 haplotypes TGFB1 — 0.05 60 vs 40 — Bulgarian Age range: 65-99 codon 10 C/C, codon 25 G/G; −988 C/C, −800 G/G — Candidate Region/Gene 21299522
1082, 819, 592 IL-10 — 0.05 17 vs 105 — Bulgarian Mean age 78.9 ACC/ATA GCC/ACC Candidate Region/Gene 15050300
  • 7 variants