Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    XRCC3 intron 3 STR 0.0005 430 (case) vs 290 British Mean age 70 15 13 Candidate Region/Gene 16518718
    XRCC5 120 bp 5` (GAPyA)n STR 0.0005 430 (case) vs 290 British Mean 70 16+2 15 Candidate Region/Gene 16518718
    SI000565Q APOB 0.001 191 (case) vs 53 Chinese > 90 baseline, Mean age 97 +/- 3 LL Candidate Region/Gene 17393087
    VNTR DC-SIGNR 0.041 361 vs 342 Chinese >90 non-6/7 genotype 6/7 genotype Candidate Region/Gene 20003397
    intron 2 VNTR IL1RN 0.08 250 vs 400 Finn >90 Candidate Region/Gene 11640949
    3'APOB-VNTR APOB 0.29 175 vs 200 Danish >100 Candidate Region/Gene 11592926
    rs4646994 ACE 0.849 399 vs 302 Chinese >90 years Candidate Region/Gene 19502260
    • 7 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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