Longevity Variant Database

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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs10085518 PSCD3 4.59e-05 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs1037381 3.99e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs10433502 FAM19A1 3.49e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs10485170 3.67e-05 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs10518142 NAAA 8.89e-06 1364 American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs10901296 ABL1 2.37e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs11206814 2.67e-05 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs12257410 FRMD4A 3.77e-05 1364 American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
    rs12562047 UCK2 2.7e-05 1364 American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
    rs12740413 ARHGEF19 1.3e-05 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs13111494 ART3 1.28e-05 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs1418425 9.64e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs1537438 2.53e-05 1364 American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs1555453 MOBKL2B 1.07e-05 1364 American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
    rs17047650 FAM19A1 3.19e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs17049647 7.12e-06 1364 American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs17205854 3.74e-06 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs17618813 ANK2 4.16e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs17811551 ADAMTS6 3.74e-06 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs1857821 NAAA 5.12e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs2271528 SDAD1 1.02e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs2444861 C8orf47 8.99e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs2710548 FAT4 2.79e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs3125524 3.83e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs3210458 ACPL2 1.52e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
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    • 25 of 710 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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