Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    (+)2019 del ADIPOQ10 0.05 118 centenarians vs 78 unrelated young Ashkenazi Jewish 95-105 A Del/Del Candidate Region/Gene 18511746
    rs72533289 KIR2DS4 1.0 180 vs 180 Irish Mean age 89 Candidate Region/Gene 15130674
    rs4646994 ACE 0.04 227 Uighur individuals, 108 Kazakh individuals, and 89 Han individuals Chinese Old: 59-70, Very old 90-113 I (insertion) Candidate Region/Gene 11773214
    SV-6 CLU 1.0 49 vs 27 vs 20 Greek, Italian 99–107 Candidate Region/Gene 16804001
    rs4646994 ACE 2.25 0.003 834 Brazilian 10-104 I D (only for Gaucho population) Candidate Region/Gene 14528043
    • 5 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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