Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    mtDNA haplotype 0.0052 212 vs 275 Italian 100+ non-J haplogroups Mitochondrial Haplogroup 10463944
    mt9055A mtDNA 0.164 129 vs 100 Irish 80-97 Mitochondrial Haplogroup 11404057
    C150T mtDNA L2 1.0 556 vs. 403 Chinese 90-108 Mitochondrial Haplogroup 21262335
    Mitochondrial haplogroups mtDNA 0.001 225 (cases) vs 400 middle aged vs 257 infants Finn 90-91 H U, J, K Mitochondrial Haplogroup 12483296
    5178A,10400T mtDNA 0.387 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    3010A,5178A,10400T mtDNA 0.141 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    14979C,3010A,5178A,10400T mtDNA 0.781 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    8020A,3010A,5178A,10400T mtDNA 0.549 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    8964T,8020A,3010A,5178A,10400T mtDNA 0.319 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    9296T,8964T,8020A,3010A,5178A,10400T mtDNA 0.55 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    1107C,5178A,10400T mtDNA 0.559 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    14569A,10400T mtDNA 0.796 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    4833G,14569A,10400T mtDNA 0.949 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    7600A,4833G,14569A,10400T mtDNA 0.153 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    9824C,10400T mtDNA 0.955 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    12811C,9824C,10400T mtDNA 0.587 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    7196A,10400T mtDNA 0.847 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    8684T,7196A,10400T mtDNA 0.457 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    13263G,7196A,10400T mtDNA 0.485 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    4491A,3705G,10400T mtDNA 0.027 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    10646A,10400T mtDNA 0.753 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    5417A,10873T mtDNA 0.018 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    12358G,5417A,10873T mtDNA 0.058 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    1736G,10873T mtDNA 0.288 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
    3970T,12705C,10873T mtDNA 0.147 463 vs 1389 Chinese >/=95 Mitochondrial Haplogroup 19641616
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    • 25 of 36 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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