Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (1027)   No Age Effect (543)  
  • Study type: + -
    GWAS (2)   ‑ (27)   Candidate Region/Gene (784)   Meta‑Analysis (38)   Complete Mitochondrial Genome (2)   Whole‑Genome Linkage Scan (1)   Genome‑Wide Association Study (710)   Mitochondrial Haplogroup (36)   Mitochondrial genome (3)  
  • Variant type: + -
    SNP (572)   Locus (5)   Haplotype (87)   Other (1)   STR (11)   Deletion (5)   CNV (1)    (1)   VNTR (1)  
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs1799983 NOS3 — 0.703 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
    rs2297518 NOS2 — 0.066 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
    rs2682826 NOS1 — 0.589 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
    rs1853432 JUN — 0.52 213 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs17356414 JUN — 0.082 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs1815274 JUN — 0.18 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs2511837 CBL — 0.14 212 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs7914 CBL — 0.69 190 vs 376 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs2249466 CBL — 0.9 207 vs 394 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs11217184 CBL — 0.8 212 vs 396 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs12786104 CBL — 0.12 210 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs738288 ATF4 — 0.54 205 vs 396 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs6519194 ATF4 — 0.41 206 vs 397 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs8192290 SOD3 — 0.428 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs8192291 SOD3 — 0.144 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs2536512 SOD3 — 0.942 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs1007991 SOD3 — 0.679 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs17881426 SOD3 — 0.425 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs699473 SOD3 — 0.613 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs8192287 SOD3 — 0.955 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs6857 PVRL2 0.90 0.518 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
    rs519113 PVRL2 0.90 0.3734 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
    rs395908 PVRL2 0.81 0.048 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
    rs11879589 PVRL2 1.67 0.07601 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
    rs4803766 PVRL2 0.97 0.708 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
    • Page 1 of 66
    • 25 of 1635 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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