Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (3)   No Age Effect (5)  
  • Study type: + -
    Candidate Region/Gene (8)  
  • Variant type: + -
    SNP (5)  
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs1501299 ADIPQO — 0.02 110 vs 120 — Jordanian mean age 90.2 years T G Candidate Region/Gene 20201642
    rs7799039 LEP — 0.02 110 vs 120 — Jordanian mean age 90.2 years C A Candidate Region/Gene 20201642
    rs1800896 IL10 — 0.031 119 vs 118 — Jordanian Mean age 90.2 G A Candidate Region/Gene 20518833
    rs2241766 ADIPQO — 0.164 110 vs 120 — Jordanian mean age 90.2 years G T Candidate Region/Gene 20201642
    rs5746098 SOD2 — 0.355 130 vs 135 — Jordanian Mean age 90.01 — — Candidate Region/Gene 20003469
    rs266729 ADIPQO — 0.635 110 vs 120 — Jordanian mean age 90.2 years G C Candidate Region/Gene 20201642
    rs1801133 MTHFR — 0.727 130 vs 135 — Jordanian Mean age 90.01 — — Candidate Region/Gene 20003469
    rs1800629 TNF — 1.0 119 vs 118 — Jordanian Mean age 90.2 — — Candidate Region/Gene 20518833
    • 8 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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