Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs507879 CASP5 1.4e-05 510 vs 549 Russian 75–103 AG AA, GG Candidate Region/Gene 20434535
    T-455C APOC3 0.005 183 vs 110 Russian 70-106 T C Candidate Region/Gene 11193221
    rs4673 1.48 0.022 Russian C T Candidate Region/Gene 23755540
    APOC3 T455C APOC3 0.05 147 elderly individuals (70–106 years old) Russian mean age: 84.6 years Candidate Region/Gene 11193221
    • 4 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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