Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs1887922 IDE 2.02 0.0004 829 vs 1033 Australian, Caucasian Mixed Candidate Region/Gene 18448515
    rs2251101 IDE 1.88 0.0011 829 vs 1033 Australian, Caucasian Mixed Candidate Region/Gene 18448515
    5-HTTLPR SLC6A4 0.03 15 male, 53 female centenarians (cases) Australian, Caucasian 101.0 ± 0.2 L/L (only for males) Candidate Region/Gene 22985157
    • 3 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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