Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):


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    Populations | Study Types | Variant Types



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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs5491 ICAM1 5e-66 5036 American 28-70 TT, AT AA Genome-Wide Association Study 22174011
    rs9330200 TUBB4B 6e-53 5036 American 28-70 AA, AT TT Genome-Wide Association Study 22174011
    rs2292664 RIMBP2 1.4e-37 5036 American 28-70 CC, CG GG Genome-Wide Association Study 22174011
    rs4537545 IL6R 3e-18 308 American, European, Ashkenazi Jewish 75.7 Candidate Region/Gene 19249341
    HRAS1 LASS1 (CGT) APOE 1.06e-09 68 vs 68 American Candidate Region/Gene 20569235
    rs1528753 8.1e-08 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs4936894 VWA5A 1.11 3.38e-07 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American A Genome-Wide Association Study 21782286
    HRAS1 LASS1 (CGT) APOE 6.91e-07 204 vs 251 American Candidate Region/Gene 20569235
    HRAS1 LASS1 (CGT) APOE 1e-06 79 vs 88 American Candidate Region/Gene 20569235
    rs10493513 1.5e-06 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs12042640 Intergenic 1.09 1.71e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American T Genome-Wide Association Study 21782286
    rs2371208 2.6e-06 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs10493514 2.8e-06 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs10412199 ATCAY 0.91 3.02e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American A Genome-Wide Association Study 21782286
    rs987839 SLCO1B1 3.19e-06 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs16852912 Intergenic 1.18 3.37e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American T Genome-Wide Association Study 21782286
    rs8001976 Intergenic 1.09 3.43e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American T Genome-Wide Association Study 21782286
    rs17149227 Intergenic 0.79 3.56e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American T Genome-Wide Association Study 21782286
    rs3128591 Intergenic 0.92 3.64e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American A Genome-Wide Association Study 21782286
    rs17205854 3.74e-06 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs17811551 ADAMTS6 3.74e-06 1364 American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs11582903 Intergenic 1.12 3.94e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American A Genome-Wide Association Study 21782286
    rs11162963 Intergenic 1.09 4.15e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American T Genome-Wide Association Study 21782286
    rs4850695 Intergenic 1.09 4.62e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American A Genome-Wide Association Study 21782286
    rs1857821 NAAA 5.12e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    • Page 1 of 13
    • 25 of 303 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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