Longevity Variant Database

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  • Variant type: + -

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    Populations | Study Types | Variant Types



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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs1857821 NAAA 5.12e-06 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs10518142 NAAA 8.89e-06 1364 American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs2271528 SDAD1 1.02e-05 1364 American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs13111494 ART3 1.28e-05 1364 American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs4859571 NAAA 1.56e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs2710548 FAT4 2.79e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs6532496 PDLIM5 4e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs17618813 ANK2 4.16e-05 1364 American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs795602 MGST2 0.67 4.52e-05 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs765850 APBB2 1.10 0.000259753 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs2660342 LOC285429 1.23 0.000314442 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs1517598 PROM1 1.44 0.000445256 801 vs 914 Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs6812745 SORCS2 1.21 0.000558765 801 vs 914 Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs4647992 NFKB1 1.81 0.000608192 801 vs 914 Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs1230155 METAP1 1.20 0.000611098 801 vs 914 Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs7656234 SLC4A4 1.16 0.000700593 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs358256 GBA3 1.12 0.001136273 801 vs 914 Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs750032 PPP3CA 0.0029 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 Genome-Wide Association Study 14615589
    rs10937739 PPP2R2C 0.00404 1173 vs 570 American 85-100 T Genome-Wide Association Study 22533364
    • 19 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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