Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    11 different snps tested, not all given. MTTP 1.0 1398 vs 777 British 77.9 ± 0.2 Candidate Region/Gene 17339647
    Not specified IL2 0.05 470 vs 120 Italian, Bulgarian Age range: 65-99 Candidate Region/Gene 21299522
    -330T/G IL2 1.43 0.096 168 vs 214 Italian >99 Candidate Region/Gene 16518704
    rs2866164 MTTP 0.05 126 vs 288 Ashkenazi Jewish median age = 97 CG/GG Candidate Region/Gene 22496539
    rs10014396 SNCA 0.021 769 total (see notes) Caucasian >90 (oldest age group) C Candidate Region/Gene 22912757
    rs3775439 SNCA 0.025 769 total (see notes) Caucasian >90 (oldest age group) A Candidate Region/Gene 22912757
    rs356218 SNCA 0.53 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs17180453 SNCA 0.63 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs3775423 SNCA 0.9 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2736990 SNCA 0.31 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2572324 SNCA 0.41 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs3796661 SNCA 0.59 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2737033 SNCA 0.27 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs9995651 SNCA 0.98 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2583959 SNCA 0.21 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2737012 SNCA 0.21 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs1372519 SNCA 0.19 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs3756063 SNCA 0.54 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs1372520 SNCA 0.22 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2619361 SNCA 0.26 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2619362 SNCA 0.27 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2301135 SNCA 0.79 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2619363 SNCA 0.24 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs2583988 SNCA 0.26 769 total (see notes) Caucasian >90 (oldest age group) Candidate Region/Gene 22912757
    rs750032 PPP3CA 0.0029 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 Genome-Wide Association Study 14615589
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    • 25 of 60 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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