Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    ADA genotypes ADA 0.003 62 vs 64 vs143 vs 272 Italian Minimum age 90 ADA*2 non-ADA*2 Candidate Region/Gene 20174870
    rs73598374 ADA 1.94 0.036 261 vs 144 Italian 66-88 G*/G* A*+ Candidate Region/Gene 21865054
    rs2070325 LPLUNC4 2.42 5.98e-05 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs2024714 CDH4 7.43e-05 1173 vs 570 American 85-100 C Genome-Wide Association Study 22533364
    rs6105966 C20orf79 1.22 0.000131258 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs4596036 PREX1 1.12 0.00066782 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    • 6 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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