Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):


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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    Not specified IFNG 0.05 707 vs 339 Turkish, Polish, Italian, Bulgarian Age range: 65-99 Candidate Region/Gene 21299522
    rs2071069 TPI1 0.05 1422 vs 967 German mean age: 98.8, age range: 95–110 (SNP is G/A) Candidate Region/Gene 18510744
    rs2071065 TPI1 0.05 1422 vs 967 German mean age: 98.8, age range: 95–110 (SNP is T/C) Candidate Region/Gene 18510744
    rs1800802 MGP 0.77 0.132 137 vs 213 Korean Mean age 90 C Genome-Wide Association Study 19641380
    Cdx2-GATA haplotype 1 allele Vitamin D receptor 0.78 935 participants Dutch mean age = 75.7 years Candidate Region/Gene 21051524
    microsatellite polymorphism surrounded by rs2288377, rs5742612, and rs35767 IGF1 0.922 493 vs 425 Chinese (females ≥ 94; males ≥ 90 Candidate Region/Gene 20199671
    rs2288377 IGF1 1.0 485 vs 392 Chinese 94.92 Candidate Region/Gene 18761080
    rs5742612 IGF1 1.0 485 vs 392 Chinese 94.92 Candidate Region/Gene 18761080
    rs35767 IGF1 1.0 485 vs 392 Chinese 94.92 Candidate Region/Gene 18761080

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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