Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs12413082 MSRB2 0.53 3.33e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs7915479 CDH23 1.92 2.81e-05 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs1556758 SORCS1 0.50 3.47e-05 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs12257410 FRMD4A 3.77e-05 1364 American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
    rs3758391 SIRT1 1.45 0.026 246 vs 236 Chinese 60-90 C Candidate Region/Gene 20633545
    rs740746 ADRB1 0.556 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 Candidate Region/Gene 23020224
    • 6 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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