Longevity Variant Database

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    Populations | Study Types | Variant Types



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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs12413082 MSRB2 0.53 3.33e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs7915479 CDH23 1.92 2.81e-05 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs1556758 SORCS1 0.50 3.47e-05 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs12257410 FRMD4A 3.77e-05 1364 American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
    rs1516507 KCNMA1 1.36 9.67e-05 403 vs 1670 3746 vs 5912 Dutch Mean age 94 G Genome-Wide Association Study 21418511
    rs4751140 EBF3 1.21 0.000268865 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs982764 FAS 1.10 0.000335327 801 vs 914 Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs4918255 SORCS1 1.27 0.00063068 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs11005328 ZWINT 3.16 0.002342056 801 vs 914 Caucasian Median age 104 A C Genome-Wide Association Study 22279548
    rs10509271 CTNNA3 1.21 0.002944036 801 vs 914 Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    • 10 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


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