(A/C)−110

Polymorphism: (A/C)−110


Location: 6p21.3

Factor:
- Symbol: HSP70-1
- Name: heat shock 70kDa protein 1A
- Entrez ID: 3303
- Ensembl ID: ENSG00000204389

Factors:

HSP70-1 heat shock 70kDa protein 1A ( 3303 / ENSG00000204389 )

Ethnicity: Italian
Age of cases: 100 years and above
Shorter lived allele: A

Statistics
- Number of cases/controls: 120 vs 471 (initial)
- Odds ratio: 0.403
- p-value: 0.005 [0.005]
- Significant: yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
14501185: The allele (A)(-110) in the promoter region of the HSP70-1 gene is unfavorable to longevity in women.

Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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