XbaI

Polymorphism: XbaI


Variant Type: SNP
Location: 2p24-p23

Factor:
- Symbol: APOB
- Name: apolipoprotein B (including Ag(x) antigen)
- Entrez ID: 338
- Ensembl ID: ENSG00000084674

Factors:

APOB apolipoprotein B (including Ag(x) antigen) ( 338 / ENSG00000084674 )

Description:

Rsid is rs693 Allele frequencies didn`t differ significantly between age groups. However X+X+ (genotype) were enriched in long-living people

Ethnicity: Chinese
Age of cases: > 90 baseline, Mean age 97 +/- 3
Longer lived allele: X+X+
Finding: Positive

Statistics
- Number of cases/controls: 191 (case) vs 53 (initial)
- Odds ratio: 1.296
- Odds ratio type: Longer
- p-value: 0.03 [0.03]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Restrictive enzyme Xba I, Taq polymerase

Reference:
17393087: Correlation between haplotype of apolipoprotein B gene and natural longevity persons in Uygur nationality.

Choice: Clean
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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