XRCC3 intron 3 STR

Polymorphism: XRCC3 intron 3 STR





Variant Type: STR
Location: 14q32.3


Factors:
  • XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 ( 7517 / ENSG00000126215 )


  • Description:

    STR length polymorphism at XRCC3 at intron 3. Possibly it`s rs371038395.

    Ethnicity: British
    Age of cases: Mean age 70
    Shorter lived allele: 15
    Longer lived allele: 13
    Finding: Positive

    Statistics
    - Number of cases/controls: 430 (case) vs 290 (initial)
    - p-value: 0.0005 [0.425]
    - Significant: Yes

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: ABI Prism 310 Genetic Analyser

    Reference:
    16518718: Genotype profiles of loci encoding DNA repair enzymes in newborn and elderly populations: no evidence of association with longevity.

    Choice: Clean
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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