DR13

Polymorphism: DR13


Location: 6p21.3

Factor:
- Symbol: HLA-DRB1
- Name: major histocompatibility complex, class II, DR beta 1
- Entrez ID: 3123
- Ensembl ID: ENSG00000196126

Factors:
  • HLA-DRB1 major histocompatibility complex, class II, DR beta 1 ( 3123 / ENSG00000196126 )


  • Description:

    DR13's frequency was increased in centenarians of both genders [OR = 1.46 (1.2–1.75)].

    Ethnicity: French

    Statistics
    - Number of cases/controls: 325 centenarians versus 229 nonagenarian siblings (initial)
    - p-value: 0.01 [<0.01]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: -
    - Technology:

    Reference:
    9425225: HLA-DR alleles display sex-dependent effects on survival and discriminate between individual and familial longevity.

    Choice:
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 26, 2013, 1:39 p.m.

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