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Polymorphism: -


Location: 11p15.5

Factor:
- Symbol: TH
- Name: tyrosine hydroxylase
- Entrez ID: 7054
- Ensembl ID: ENSG00000180176

Factors:
  • TH tyrosine hydroxylase ( 7054 / ENSG00000180176 )


  • Description:

    southern Italy (n=92 centenarians, age range 100–108 years old, mean 101.9; and n=97 controls aged 20–60 years old, mean 41.44), northern-central Italy (n=307 centenarians, age range 99–109 years old, mean 101.0; and n=352 controls aged 17–60 years old, mean 41.2), Germany (n=376 centenarians, age range 100–110 years old, mean 104.41; and 376 controls aged 60–75 years old, mean 67.52) and France (n=546 centenarians, age range 99–106 years old, mean 103.1; and 315 controls aged 18–70 years old, mean 51.2).

    Ethnicity: French, German, Italian
    Age of cases: centenarians; see notes

    Statistics
    - Number of cases/controls: see notes; stratified by population; total = 1321 cases versus 1140 controls (initial)
    - p-value: 0.05 [>0.05]
    - Significant: no

    Study Design
    - Classifications: No Age Effect
    - Study type: -
    - Technology: SNPlex technology

    Reference:
    19367319: Human longevity and 11p15.5: a study in 1321 centenarians.

    Choice: Curate
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 26, 2013, 1:37 p.m.

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