K153R

Polymorphism: K153R


Location: 2q32.2

Factor:
- Symbol: MSTN
- Name: myostatin
- Entrez ID: 2660
- Ensembl ID: ENSG00000138379

Factors:

MSTN myostatin ( 2660 / ENSG00000138379 )

Ethnicity: Spaniard
Age of cases: Range : 100-111
Shorter lived allele: K
Longer lived allele: R

Statistics
- Number of cases/controls: 156 vs 384 (initial) | 79 vs 316 (unelated Italian cohort) (replication)
- Odds ratio: 3.48
- p-value: 0.001 [0.001]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene

Reference:
23354683: Association of the K153R polymorphism in the myostatin gene and extreme longevity.

Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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