rs4646994

Polymorphism: rs4646994
rs4646994 ( SNPedia | 23andMe )

Variant Type: STR
Location: 17q23.3

Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640

Factors:

ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1636 / ENSG00000159640 )

Description:

"No association of the ACE gene insertion/deletion polymorphism with longevity was observed in our Han Chinese population" Detailed P-value data: No significant differences were observed between the two groups in the distribution of Genotypes (Overall: 0.849, Adjust for gender: Male, 0.994; Female, 0.797) and Alleles (Overall: 0.849, Adjust for gender: Male, 0.969; Female, 0.884)

Trivial name is ACE Alu insertion/deletion.

Ethnicity: Chinese
Age of cases: >90 years
Finding: Negative

Statistics
- Number of cases/controls: 399 vs 302 (initial)
- p-value: 0.849 [0.849]
- Significant: No

Study Design
- Classifications: No Age Effect
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
19502260: Lack of genetic association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and longevity in a Han Chinese population.

Choice: Clean
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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